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One commenter noted the benefit of less-specific criteria for inclusion in the numerator and denominator, which would provide flexibility for the measure to remain relevant to current circumstances, while others raised concerns over measure specifications, including using the concept of up to date given the evolving definition of the term, the fact that patient refusals are not excluded, and the frequency of data submission

doi: 10.1007/s11064-018-2641-5 32 DinkinsM

Specifically, following treatment with drugs, the male mice were co-caged for 2 months to test their reproductive ability

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