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Migliavacca" Center for Liver Disease, Department of Pathophysiology and Transplantation, University of Milan, (14)Hepatology and Liver Transplant Unit, Azienda Sanitaria Universitaria Integrata Di Udine, (15)Gastroenterology Unit, Fondazione Casa Sollievo Della Sofferenza Irccs San Giovanni Rotondo, (16)Internal Medicine, Azienda Ospedaliero-Universitaria "Maggiore Della Carit", (17)Department of Translational Medicine (DiMeT), Universit Del Piemonte Orientale, (18)SC Infectious Diseases, Asst Papa Giovanni XXIII, (19)Department of Precision Medicine, University of Campania "Luigi Vanvitelli", (20)Division of Hepatogastroenterology, Department of Precision Medicine, Universit Della Campania "Luigi Vanvitelli", Naples, Italy, (21)Uoc Infectious Diseases, Ospedale Umberto I Di Siracusa Background: Compulsory hepatitis B virus (HBV) vaccination greatly reduced new hepatitis D virus (HDV) infections in native Italians

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1), each with unique regulatory mechanisms that influence physiological and pathological processes, including immune responses and tissue damage [3]