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CAR-T cells have a particular effect in treating solid tumors such as renal cell carcinoma, HER2 positive sarcoma, ovarian cancer (94), and colorectal cancer (95)

Arch Biochem Biophys 525: 102-110

CAR-T cell expansion showed dose-dependent kinetics, with responses deepening at higher dose levels

LAT1 is overexpressed in several cancers, including glioblastoma [76], brain metastases [77], and various solid tumors, as well as in neurological disorders, such as autism spectrum disorders [78]