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Epigenetic changes in renal genes dysregulated in mouse and rat models of type 1 diabetes

in diabetic patients (Millen et al., 2004)

A deeper mechanistic understanding of how systemic signals modulate ferroptosis-immune crosstalk in vivo may enable the development of therapeutic strategies that precisely recalibrate necroinflammatory pathways, thereby delineating how targeted modulation of necroinflammatory pathways can be leveraged to uncouple cell death from adverse immune effects and thereby refine future therapeutic strategies

In this study, dietary ALA would have been available to all retinal cells, and therefore capable of increasing antioxidants globally