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Regulatory and Compliance Risk : The Food and Drug Administration (FDA) classified BPC-157 under Category 2 in 2023, prohibiting its legal compounding due to insufficient safety data

Some of the studies involved high doses that came with a hefty dose of side effects

Clinical Principle If the usual IC/BPS therapies provide no improvement in symptoms, then the clinician should revisit the diagnosis of IC/BPS and consider whether an unidentified disorder may be present that is producing symptoms

Understanding the specific manifestations and shared mechanisms of BBB breakdown in prevalent neurodegenerative diseases opens new research and therapeutic opportunities