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Additionally, AMDs pathogenesis involves the loss of RPE-derived VEGF signaling and defenestration of usually high permeable choriocapillaries in atrophied RPE areas, which disrupts retinal permeability [440, 441]

Cancer Res 65(8):3307-3318, 2005

(2022) 8:eabo5633

The concordance of our patient's serologic profile and clinical course with these reports supports the consistency of methimazole-induced lupus as a recognizable clinical entity in pediatrics and highlights the importance of vigilance, particularly in the first few weeks of treatment