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The normalization algorithm is based on PCA with some advantages: it allows simultaneous normalization of data sets of spectra by identifying signals affected by the agent (in this case, after the diet regimen) and quantitative measurement of variations

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A unique type of sugar made in the body from glucose, ribose plays important roles in the production of RNA and DNA, as well as ATP (adenosine triphosphate), the primary energy source for every cell in the body

Apoptosis assay To verify the impact of free DTX and DTX-loaded MeO-PEG-b-(NIPAAm-co-PBAE) NPs on apoptosis promotion, an apoptosis assay was further assessed by the Ex-bioscience apoptosis detection as reported by the manufacturers protocol