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Despite these differences, research has shown that even low doses of ionizing radiation produce cellular responses (double stranded breaks, free radical formation, lipid peroxidation, cellular necrosis, apoptosis) that are analogous, albeit smaller, than larger radiation doses [58]

Ferroptosis inducers can potentiate immunotherapy by triggering immunogenic cell death, releasing tumor antigen and activating antitumor immune responses

However, this increased dose also resulted in higher levels of Cyp3A4-derived Amb metabolites, whose clinical implications remain unclear

Effects of anti-glutamic acid decarboxylase antibodies associated with neurological diseases