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After removing the final wash, the beads were incubated twice at room temperature in 80 l of the digestion buffer (2 M urea, 50 mM Tris-HCl, 1 mM DTT and 0.4 g of trypsin) while shaking at 1,000 rpm

The numbers of fungal transcripts were significantly higher from 12 dpi with V991 compared to those with 1cd3-2, indicating that the fungal biomass of V991 in the host was higher than that of 1cd3-2 at the late stage of infection (Supplementary Fig

Since the current interventions address the outcome (via renal replacement therapy), a comprehensive elucidation of the biological and molecular mechanisms underlying kidney fibrosis is urgently needed to facilitate the development of disease-modifying therapies

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