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We demonstrate that these recombinant proteins when administered intravenously in a thrombocytopenic mouse model, were effectively recruited to injury sites, enhanced fibrinogen deposition, and significantly reduced bleeding without inducing pathological thrombus formation

GHK-Cu (glycyl-L-histidyl-L-lysine copper(II) complex) is a naturally occurring copper-binding tripeptide first identified in human plasma in 1973

doi: 10.1016/j.chom.2015.06.002

5.1.2 Thioredoxin reductase Thioredoxin reductase (TrxR) is a homodimeric enzyme that boasts a sophisticated architecture, featuring a flavin adenine dinucleotide (FAD) and a reduced nicotinamide adenine dinucleotide phosphate (NADPH) binding site for each of its monomers, thereby facilitating its essential role in cellular redox homeostasis (183)