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In three-dimensional collagen gel models that mimic tissue environments, fibroblasts treated with GHK-Cu demonstrate enhanced migration and matrix remodeling capabilities, essential for proper wound closure and tissue integration

& Weiner, M

Specifically, its introduction into potatoes led to a quantifiable increase in the tubers protein content compared to non-modified potatoes, while its expression in maize enhanced the grains nutritional quality versus standard maize, without causing allergic reactions in animal models or consumers (Luna-Surez et al., 2010

In vivo, M1 macrophage exosomes with low miR-663b expression attenuated pulmonary vascular remodeling in PH rats, suggesting that exosomal miR-663b exacerbates PASMC dysfunction and PH progression by suppressing the AMPK/SIRT1 axis and promoting inflammation