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The human solute-carrier gene ( SLC ) superfamily comprises a large number (at least 362) of putatively functional, protein-coding genes that can be divided into 55 gene subfamilies encoding membrane-bound transporters

Hutchison WM, Aitken PP, Wells BW (1980)

ENTERPRET: a randomized controlled trial of Vedolizumab dose optimization in patients with ulcerative colitis who have early nonresponse

Iron chelators (like deferoxamine), ROS scavengers (like N-acetylcysteine) and the canonical ferroptosis inhibitor ferrostatin-1 all attenuate this cascade, underscoring the central role of microglia-driven iron dysregulation in SCI pathology ( Ferroptotic microglia themselves amplify inflammation