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Two individuals who started the regimen at approximately the same time as the four, but who dropped out, succumbed within 6 months

Notably, ACSL4-driven lipid peroxidation is significantly potentiated under GPX4 deficiency (Wang R

Since this SSE is associated with a loss of sensitivity and accuracy, the above-mentioned sample preparation methods describe compromises between the minimization of these matrix effects by removing matrix components during sample clean-up, and the ability to detect a broad spectrum of analytes with reasonable sample preparation efforts and adequate sensitivity

S., Wang, H., Zhuo, P., Schwartz, J