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found that the combination of PTT with immunogenic coreshell Au@Se NPs could enhance the positive expression of Hsp70 in cancer cells, and Au@Se NPs could effectively stimulate the maturation of DCs with antigen-presenting functions, reminding us the potential application of Se NPs in antitumor immunity ( Figure 2 Se NPs enhance natural killer cell functions Natural killer (NK) cells play a vital role in innate immune responses to cancer and infection, which is highly related to their surface receptors for recognizing tumor cells and pathogen-infected cells, leading to the activation of receptor-triggered cytotoxicity and cytokine production

De novo design of luciferases using deep learning

Ethics statement The studies involving humans were approved by Ethics Committee of the Area Vasta Nord Ovest Toscana (Italy)

The Centre has conducted studies in collaboration with several companies including GSK, Pfizer, Wyeth and Mead Johnson