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In the 12-week randomised controlled trial documented in the obesity pharmacotherapy literature, the 1 mg/day group achieved statistically meaningful separation from placebo

AOD 9604 best clinical result was approximately 2.8kg of additional fat loss over 12 weeks, and the larger confirmatory trial (OPTIONS study, 536 subjects, 24 weeks) failed to show statistically significant weight loss compared to placebo

Product Overview 5-Amino-1-methylquinolinium (5-Amino-1MQ) is a small molecule inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme involved in NAD+ metabolism and cellular energy regulation

Alternative mechanisms currently under investigation appear to include potentially peptide-related modulation of energy expenditure and fatty acid oxidation pathways