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Since inflammation of the large intestine affects brain function through braingut interaction, patients with colitis are at a high risk of developing psychiatric disorders, such as depression and anxiety, during the exacerbation period 43,44

Further observations suggested that gustducin may be one, but not the only player in sweet taste transduction, since: (1) only a subset of sweet taste receptor expressing cells are positive for gustducin, with publications reporting from 1/10 to 2/3 of double positive cells (Hoon et al., 1999

Oral glutathione supplements can be helpful, though absorption may vary (liposomal formulations generally have higher bioavailability)

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