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Even in healthy athletes, the build-up of ammonia can lead to extreme fatigue and dementia because it reduces glycogen formation and inhibits the energy cycle

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Gut bacteria that prevent growth impairments transmitted by microbiota from malnourished children

Another amino acid, glutamine, has very little research on its possible nootropic effects, but one literature review suggests that supplementation may be able to improve mood and cognition in cases of high-altitude hypoxic stress (low levels of oxygen in your body from living in or visiting high-altitude regions).71 72 Vitamins and minerals Often affecting mood and cognition, fatigue and brain fog are highly prevalent symptoms of vitamin and mineral deficiencies