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The inhibition of mitogen-activated protein kinases (MAPKs) and NF-B underlies the neuroprotective capacity of a cinnamon/curcumin/turmeric spice blend in A-exposed THP-1 cells

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This data strongly supports the functional medicine approach of using daily, spaced doses of charcoal to continuously "dialyze" the gastrointestinal tract and lower the overall systemic toxic burden in chronically ill patients

These include apixaban, rivaroxaban, and edoxaban (direct inhibitors of factor Xa), and dabigatran (direct inhibitor of thrombin [factor IIa])