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doi: 10.1371/journal.pcbi.1007996 14

Key Nutrient Deficiencies That Contribute to Anxiety B Vitamins (B12, B6, and B9 - Folate) Vitamin B12 : Critical for the synthesis of neurotransmitters Deficiency causes neurological symptoms Affects myelin production Maintains nerve cell health Involved in the metabolism of homocysteine Vitamin B6 : Participates in the synthesis of serotonin Regulates dopamine levels Helps in the production of GABA Necessary for amino acid metabolism Supports immune function B9 (Folate) : Essential for DNA methylation Supports neurotransmitter production Regulates gene expression Involved in the synthesis of S-adenosylmethionine

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