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It also enhances the accumulation of lipid peroxides and alters proteins associated with ferroptosis, such as GPX4, which ultimately result in the ferroptosis of chondrocytes (80, 160)

However, other evidence contradicts these findings, further noting that sulfites are found in many other everyday food items that dont trigger headaches [16]

Additionally, thiamin triphosphate (TTP) may be involved in neuronal membrane functions and nerve impulse (action potential) generation, but the exact biochemical role of TTP is still not well understood (22, 23)

Robertson RM et al (1982): Exacerbation of vasotonic angina pectoris by propranolol