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doi: 10.1111/j.1468-3083.2012.04700.x

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S Fiorucci A Carino M Baldoni L Santucci E Costanzi L Graziosi E Distrutti M Biagioli 2021 Bile acid signaling in inflammatory bowel diseases Dig Dis Sci 66 3 674 693 KB Islam S Fukiya M Hagio N Fujii S Ishizuka T Ooka Y Ogura T Hayashi A Yokota 2011 Bile acid is a host factor that regulates the composition of the cecal microbiota in rats Gastroenterology 141 5 1773 1781 Sayin SI, Wahlstrom A, Felin J, Jantti S, Marschall HU, Bamberg K, Angelin B, Hyotylainen T et al (2013) Gut microbiota regulates bile acid metabolism by reducing the levels of tauro-beta-muricholic acid, a naturally occurring FXR antagonist

Figure 1 2.1 APOE4 and Parkinsonism Notably, clinically and pathologically, there is significant overlap between AD and PD, suggesting that they may have common underlying mechanisms