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In the latter conformation, the rAmy bypass motif becomes disordered, enabling the receptor ECD to adopt a position similar to CT-bound CTR or AMYR complexes 15

In contrast, vital NETosis ends up with the production of a DNA-filled vesicle that fuses with the outer membrane to release NETs [125, 131]

Hyperuricemia treatment in acute heart failure patients does not improve their long-term prognosis: A propensity score matched analysis from the AHEAD registry