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10.1038/cddis.2016.105 43 PossematoR.MarksK

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Luciferase reporter assays showed that ectopic expression of Np63, but not the transactivation defective mutant (R304W), promoted reporter activity of PHGDH-Gluc, PSAT1-Gluc, PSPH-Gluc, SLC1A4-Gluc (Fig

Extracellular NAMPT and NAPRT: Adipocytokines and DAMPs In addition to a direct effect on NAD and its metabolites, the enzymes involved in synthesis of NAD also have important extracellular functions, as summarized in Figure 3