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However, the confounding bias here is that the reason for prescribing alpha-GPC was to prevent or slow down cognitive decline or dementia.[ref] However, the possible increase in relative stroke risk is something to take into consideration with higher levels of alpha-GPC supplements in older adults

Gradisteanu Pircalabioru, G

Pathophysiology of deep vein thrombosis

Polymorphisms of the methylenetetrahydrofolate reductase (MTHFR) gene lead to reduced methylation, elevation of Hcy, reduction of nitric oxide, microvascular disease- particularly capillary endothelial injury and apoptosis, microaneurysms, leakage, ischemia, retinal atrophy, neovascularization, and vision loss [22]