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Description

In a sepsis-induced AKI model, USP9x inhibits the ubiquitinated degradation of toll-like receptor 4 (TLR4), which is involved in inflammatory responses and apoptosis by activating the NF-B signaling pathway through interaction with lipopolysaccharide (LPS)

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Results from in vitro tests demonstrated that sustained delivery of both curcumin and puerarin lasted for 6 hours in non-reducing conditions and 5 hours in reducing conditions

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Supplementation of cobalamin is useful in neuronal regeneration

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It exerts its physiological effects by activating soluble guanylate cyclase (sGC), which elevates intracellular levels of cyclic guanosine monophosphate (cGMP) and triggers a protein kinase G (PKG) signaling cascade in vascular smooth muscle cells [64]

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