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7.48 (1.42) in FEP

In biological systems, reactive oxygen species (ROS), such as superoxide (O 2 ) and hydrogen peroxide (H 2 O 2 ), play important signaling roles but may also contribute to cellular damage and disease development

The simulated results of molecular docking indicated that GHK-Cu can directly bind to SIRT1 to form a protein complex, and the interacting residues in the complex are composed of GLU-230 and ASN-226 (Figure 5E)