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Cell biology of spinal cord injury and repair

Molnar J, et al

Why GCLC matters GCLC encodes the catalytic subunit of glutamate-cysteine ligase, the enzyme that catalyzes the first and rate-limiting step of glutathione synthesis

Forty-two male C57BL/6 mice were fed either a normal diet (NC group) or a high-fat and high-cholesterol (HFC) diet (HFC group) for 16 weeks, and mice from the HFC group were later randomly divided into two groups: the first were maintained on the original HFC diet, and the second were fed a medium-chain triacylglycerol (MCT)-based ketogenic diet for 8 weeks (KD group)