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Conditions such as inflammatory bowel disease (IBD), leaky gut syndrome, celiac disease recovery, autoimmune diseases, and mast cell activation syndrome (MCAS) can be incredibly challenging to manage

10.1089/ars.2017.7230 3

The main exceptions are highly acid-sensitive or base-sensitive sequences where the pH 4.5-7.0 range of bacteriostatic water could affect stability, and some labile peptides where even the small amount of benzyl alcohol might interfere with the assay

Pickart and Thaler isolated it from human serum in 1973 and characterized it as a tripeptide that prolongs survival of normal liver cells and stimulates growth in neoplastic liver tissue 17