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For instance, in a recent Phase 3 trial of the glucagon-like peptide 1 (GLP-1) agonist semaglutide, researchers hypothesized that reducing inflammation throughout the body could head off cognitive decline in early Alzheimers

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Although the ghrelin receptor is predominantly expressed in the central nervous system, a broad expression pattern of the gene encoding the ghrelin receptor is observed in various peripheral tissues, including the thyroid, pancreas, spleen, myocardium, adrenal gland, testis, ovary, stomach, and intestinal neurons (Gnanapavan et al., 2002