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Description

sciencedirect.com Pharmacokinetics: early studies (including dog PK) explore exposure at microgram-scale dosing

Multiple senolytic strategies are in parallel development

Most patients experience minimal side effects, with the most common being mild injection site reactions that resolve quickly

Although studies have shown that FOXO4-DRI can block the binding of P53 to FOXO4, thereby promoting the apoptosis of senescent cells, the effect of FOXO4-DRI is not limited to alleviating the aging of certain organs