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What Are The Side Effects Of The Neksium 40 Mg Injection (Esomeprazole): Headache Nausea Flatulence Stomach pain Skin rash Swelling and redness at the injection site Difficulty in breathing Edema Irregular heartbeat Severe diarrhea Unusual tiredness and weakness Fever Decreased appetite Constipation What Are The Common Drug Interactions: Few medicines have been reported to interact with Neksium 40 mg Injection

Untreated Controls Preclinical injury models % reduction in healing time Tendon Transection (Rat Achilles model)50% Skin Wound Closure (Alkali burn model)45% Muscle Crush Injury (Rat quadriceps)40% Safety Data Safety Profile from Research What preclinical and early clinical studies report Preclinical Safety Summary LD50Not achieved Acute toxicityNone observed Chronic toxicityNone in 6-month studies Organ toxicityNone detected Human IV pilot (n=2)No adverse effects Cardiac/hepatic/renalNo effects detected Regulatory & Risk Considerations FDA statusUnapproved drug WADA statusBanned since 2022 (S0) Human trialsPhase 1 only Long-term effectsUnknown in humans Pro-angiogenic riskTheoretical unstudied Australia/NZPrescription only No lethal dose was reached in preclinical toxicology studies

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Pre-clinical data suggests upregulation of nerve growth factor and vascular endothelial growth factor in injury models [9]