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Nevertheless, these results provide strong clinical evidence indicating that children with ASD were accompanied by oxidative stress marker aberrations, and the dysregulated oxidative stress marker profile in ASD children may offer novel insight into molecular pathways that confer vulnerability to the disease onset and/or progression

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Zhu XX, Yan YW, Chen D, Ai CZ, Lu X, Xu SS et al

As we age, NAD+ levels decline in the brain and other organs, and this decrease in NAD+ is associated with various disease states including neurodegeneration and other age-related disease