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Overall, strategies that promote beneficial probiotics and inhibit harmful bacteria provide promising new approaches for the treatment of ALD

Nature 575:688692 Doll S, Freitas FP, Shah R, Aldrovandi M, da Silva MC, Ingold I, Goya Grocin A, Xavier da Silva TN, Panzilius E, Scheel CH et al (2019) FSP1 is a glutathione-independent ferroptosis suppressor

The mitochondrial workload MOTS-c creates will exhaust available NAD+ faster than baseline metabolism, reducing the magnitude and duration of AMPK's effects