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Vitamins and supplements like Coenzyme Q10 and L-carnitine are suggested, if theres a sign of mitochondrial issues

The conditioned medium from PD-1 inhibitor-treated HCAECs was applied to HCFs, and the results indicated that this conditioned medium reduced the activity of HCFs, evidenced by reduced -SMA expression (Figure 3I), decreased collagen secretion (Figure 3J), and lower expression levels of collagen synthesis-related genes Fn1, CTGF, Col1a1, and Col3a1 in HCFs (Figure 3K)

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These findings suggest that secondary tumors may arise as a potential side effect of pharmacological ferroptosis induction, underscoring the need for long-term experiments to assess this possibility in suitable animal models