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To date it seems that improvement in quality of life is one of the most important outcome measures.5 BE is characterized by a vicious cycle of infection, inflammation and further sputum production

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Peer review Peer review information Nature Communications thanks Rajesh Katare, Boyi Gan, Lu Cai and the other, anonymous, reviewer(s) for their contribution to the peer review of this work

It detoxifies xenobiotics and heavy metals through a reaction catalyzed by GSH S-transferases that bind them to the sulfhydryl group on the cysteine residue