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In the present study, there was observe decreased in body, testis and accessory organs weight in NaF exposed group in comparison with the control group since growth of accessory sex glands require testosterone.51 However, administration of Cyperus esculentus nut extract increases the body weight, testis and accessory organs weight, effect of CE on increasing weight of testes and epididymis agrees with the report of Amaal and Essraa.52 This could be attributed to its rich vitamin and protective role of particularly vitamin C present in CE nut against oxidative stress and morphological changes of the testicular tissues.53 Increase in testicular and epididymal weights have been observed to be an indication of higher sperm production,54 which could be due to increased androgen biosynthesis as evidenced by a significant increase in testosterone level.55 Histological examination of NaF exposed group revealed histopathological changes in the seminiferous tubules, such as disorganization in the germinal epithelium layer of seminiferous tubules and depleted spermatogenic cells

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