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Anti-CD38 antibodies mediate anti-myeloma activity through multiple mechanisms of action both in patients with RRMM and with newly diagnosed MM, although immunomodulatory effects may be greater in earlier disease settings in which the immune system has not been affected by prior treatments [85]

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AOD9604 (Anti-Obesity Drug 9604) is a synthetic peptide fragment corresponding to amino acids 177-191 of human growth hormone (hGH), with the addition of a tyrosine residue at the N-terminus

These products are released from the adipocyte into the bloodstream, where fatty acids bind to albumin for transport to tissues that oxidize them for energy