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This tumor usually occurs in an older age group and is characterized by extensive local invasion and rapid progression.[1] Patients with this tumor have poor 5-year survival rates

Graphical abstract Similar content being viewed by others Introduction Hepatocellular carcinoma (HCC) is one of the most aggressive malignant tumors with an increasing global incidence [1]

The biological roles of senescent cells are complex and likely not yet fully understood

To demonstrate whether CoQ 10 H 2 can directly inhibit PDE activity, we constructed Lineweaver-Burk plots to express the relationship between PDE activity and CoQ 10 H 2 treatment