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It is noteworthy mentioning here that IMS and the CCS value of a molecule strongly depend on its charge state [29, 37]

has developed PEGylated liposomes modified with BV2 microglial cell membranes (hFGF-21@BCM-LIP), enabling targeted delivery of liver-derived FGF-21 to AD pathological microenvironments via subcutaneous injection [99]