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10.1007/s13311-021-01130-6 Neurotherapeutics 204 ZhangL.ShimojiM.ThomasB.MooreD

doi: 10.3389/fimmu.2022.897366 23 GuMHeTYuanYDuanSLiXShenC

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In addition, according to the astrocyte-neuron lactate shuttle hypothesis, glutamate stimulated metabolism of glucose in astrocytes produces lactate which can be transferred to neurons to be utilized as fuel (Pellerin and Magistretti, 1994)