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Among these, accumulation of p62, also known as sequestosome 1 (SQSTM-1) and A170 (119), sequesters Keap1 into aggregates, resulting in the inhibition of Keap1-mediated Nrf2 ubiquitination and its subsequent degradation by the proteasome (120)

Pathway and process enrichment analysis was then used to identify common differentially regulated pathways or processes in A2780 and A2780/GSTP1 cells (Supplementary Table 2)