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20 of 24 such patients were women

Risk factors that should prompt consideration of B12 deficiency include advancing age (reduced stomach acid production), strict vegan or vegetarian diets, pernicious anaemia, gastrointestinal surgery (particularly gastric bypass or ileal resection), long-term use of certain medications (metformin, proton pump inhibitors, H2-receptor antagonists), nitrous oxide exposure (including recreational use), and conditions affecting the gut such as Crohn's disease or coeliac disease

According to a separate study lasting a total of 2 years, the weight loss actually remains: In the STEP 5 trial, adults with overweight and obesity treated with weekly semaglutide subcutaneous injections lost an average of more than 15% of their body weight from baseline through 104 weeks, compared with the placebo groups less than 3% weight loss