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Identifying what a patient has already tried during their attempts to quit nicotine, as well as their mental and physical reactions to it, can help to determine what the next method of quitting can entail.[16] If one is trying to quit, it is important to recognize that the cessation process will require constant effort

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[108] The latest generation of e-cigarettes, "pod products", such as Juul, have the highest nicotine content (59 mg/mL), in protonated salt, rather than the free-base nicotine form found in earlier generations, which makes it easier for less experienced users to inhale