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5 Conclusion CHF combining RG showed better therapeutic effects than RG alone, and its renal protective effects were associated with reducing Scr, BUN, UA, and improving eGFR, as well as preventing renal fibrosis

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Additionally, recent clinical evidence has demonstrated that newly diagnosed hypothyroid individuals exhibit elevated malondialdehyde (MDA) and decreased total antioxidant capacity, supporting the link between impaired antioxidant status and heightened oxidative stress (Sultana et al

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