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Alternatively, cells can be recycled and NAD + reconstituted from its catabolic products via the salvage pathway, which is the preferential route for cells to replenish NAD pools 6,7,8,9,10 (Fig

Author contributions ZH: Conceptualization, Methodology, Software, Validation, Visualization, Writing original draft, Writing review and editing

Patients were also asked about side effects, duration of treatment, length of time before perceived benefit (if any), and duration of benefit (if present)