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Insulin-like growth factor-I regulation of luteinizing hormone (LH) receptor messenger ribonucleic acid expression and LH-stimulated signal transduction in rat ovarian theca-interstitial cells

GPX2 deletion alters endoderm in vitro differentiation To directly assess the GPX2 role in cell differentiation, we generated a homozygous GPX2 loss-of-function model in hPSCs by deleting the entire GPX2 gene (genomic coordinates, chr14:64,939,301-64,942,926, Hg38) (Fig