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In summary, although butyrate exhibits a wide variety of biological activities in different pathways including energy homeostasis, glucose and lipid metabolism, inflammation, oxidative stress, neural signaling, and epigenetic modulation in experimental settings, it remains unclear whether these findings are clinically relevant and whether the molecular pathways are activated by butyrate in humans

The scientifically accurate term for this condition is Hypothalamic-Pituitary-Adrenal (HPA) Axis Dysfunction

The scavenger receptor MARCO is required for lung defense against pneumococcal pneumonia and inhaled particles

Gupta A, Meena J, Sharma D, Gupta P, Gupta UD, Kumar S, Sharma S, Panda AK, Misra A