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As key mediators of the interaction between intestinal epithelial cells and the microbiota, ROS maintain intestinal health through multiple mechanisms, including the regulation of immune defense, barrier function, stem cell dynamics, and microbiota composition [116,117,118]

However, others propose that autophagy could serve as a process for cancer cell demise by potentially amplifying the impact of chemotherapy and radiotherapy in triggering cell death [31, 54]

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Glutathione has a broad spectrum of detoxification, which can enter the body with toxic compounds such as acrylonitrile, fluoride, carbon monoxide and heavy metal ions or carcinogens, combining and promote its eduction body outside, of these substances can be used for the treatment of the disease