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EGFR-TKIs have demonstrated superior efficacy compared to traditional platinum-based chemotherapy [6]

While respecting the wisdom of traditional medicine, modern scientific methods should be used to transform the potential of ZSS into a widely applicable, monitorable, and truly beneficial intervention for public health

Claudin-2 (CLDN2) and claudin-15 (CLDN15) are the main pore forming claudins expressed in the gastrointestinal tract and both of these claudins form cation specific pores [25, 26], permitting the paracellular transport of sodium ions

A two-step real-time quantitative PCR (RT qPCR) kit (Low ROX- SYBR Green) was purchased from Applied Biotechnology (ABT), Egypt