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This has profoundly impacted patients physical and mental well-being, significantly burdening public health systems and medical infrastructures (Lv et al., 2025)

doi: 10.1590/2359-3997000000128 104 DumontEVanhaeckeFCornelisR

In stark contrast, significant chromosome damage was evident upon treatment with the DNA crosslinking agent MMC, thus suggesting that when DNA repair is functional, FA might be causing cell death by damaging other cellular components rather than DNA